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PRMT5 promotes cancer cell migration and invasion through the E2F pathway

Wojciech Barczak1, Li Jin1, Simon Mark Carr1

  • 1Laboratory of Cancer Biology Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.

Cell Death & Disease
|July 26, 2020
PubMed
Summary

The PRMT5-E2F1 pathway regulates cell cycle control and cancer progression. Targeting this axis, involving arginine methylation of E2F1, offers a potential therapeutic strategy for cancer.

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