Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intravenous oxygenation with lactated Ringer's solution.

W O Kim1, C H Cho

  • 1Department of Anesthesiology, Yonsei University College of Medicine, Seoul, Korea.

Journal of Korean Medical Science
|June 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A randomized phase III clinical trial of weekly versus tri-weekly cisplatin-based chemoradiotherapy for locally advanced cervical cancer: results of the TACO (GCIG/KGOG 1027/THAI 2012) study.

ESMO open·2026
Same author

Involvement of autophagy in antibacterial actions of vitamin D in <i>Helicobacter pylori</i> infection: abridged secondary publication.

Hong Kong medical journal = Xianggang yi xue za zhi·2020
Same author

Editorial.

Current medicinal chemistry·2017
Same author

Adenosine A<sub>2A</sub> receptor and ERK-driven impulsivity potentiates hippocampal neuroblast proliferation.

Translational psychiatry·2017
Same author

Identification of pathogenic microRNAs in Helicobacter pylori-associated gastric cancer using a combined approach of animal study and clinical sample analysis.

Hong Kong medical journal = Xianggang yi xue za zhi·2016
Same author

The Co-regulatory Role of 5-Lipoxygenase and Cyclooxygenase-2 in the Carcinogenesis and their Promotion by Cigarette Smoking in Colons.

Current medicinal chemistry·2016
Same journal

EGFR and Its Ligands in Idiopathic Pulmonary Fibrosis: Predicting Clinical Outcomes and Molecular Endotyping Through In-Depth Analysis.

Journal of Korean medical science·2026
Same journal

<i>APOE</i> Genotype Modifies the Predictive Performance of Plasma Biomarkers for Amyloid Plaque Burden in Subjective Cognitive Decline.

Journal of Korean medical science·2026
Same journal

Two-Year Outcomes of a Randomized Controlled Trial of Nonintervention Versus Oral Ibuprofen for Patent Ductus Arteriosus in Premature Infants.

Journal of Korean medical science·2026
Same journal

Technology-Dependent Children Living at Home in Korea: A Population-Based Analysis Using NHIS Claims Data.

Journal of Korean medical science·2026
Same journal

Retracted Publications Related to Statistics: A Scopus-Based Bibliometric Analysis.

Journal of Korean medical science·2026
Same journal

Tuberculosis Development in Chronic Obstructive Pulmonary Disease: A Nationwide Population-Based Study.

Journal of Korean medical science·2026
See all related articles

Infusing oxygenated Ringer's lactate solution intravenously increased oxygen levels in rabbits. This experimental oxygenation method shows potential for treating hypoxia with hypovolemia.

Area of Science:

  • Experimental Medicine
  • Physiology

Background:

  • Hypoxia and hypovolemia are critical conditions requiring effective oxygenation strategies.
  • Central venous infusion offers a potential route for therapeutic interventions.

Purpose of the Study:

  • To investigate the efficacy of oxygenated Ringer's lactate solution administered via central venous infusion as a method of oxygenation.
  • To assess the impact of this intervention on blood oxygenation parameters in a rabbit model.

Main Methods:

  • Four rabbits were used in an experimental setup.
  • Oxygenated Ringer's lactate solutions with controlled oxygen tension (PO2 > 416.6 mmHg) and pH ( > 6.08) were prepared.
  • The oxygenated solution was infused through the central vein, and physiological parameters were monitored for one hour.

Related Experiment Videos

Main Results:

  • A statistically significant increase in arterial oxygen tension (PaO2) was observed post-infusion compared to control values.
  • Other measured parameters including pH, PaCO2, HCO3-, BE, and O2 saturation showed no significant changes.
  • The study confirmed that oxygenation could be achieved through the infusion of oxygenated Ringer's lactate.

Conclusions:

  • Central venous infusion of oxygenated Ringer's lactate can effectively increase blood oxygen levels.
  • This method holds potential clinical applicability for treating conditions involving hypoxia and hypovolemia.