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Crohn's disease--a case report
1Department of Pathology, Seoul National University Children's Hospital, Korea.
Insights
This report details a rare pediatric case of Crohn's disease in a 10-year-old girl presenting with severe gastrointestinal symptoms. The findings highlight typical Crohn's disease pathology, including transmural inflammation and granulomas, despite its rarity in Korea.
Area of Science:
- Pediatric Gastroenterology
- Inflammatory Bowel Disease
- Surgical Pathology
Background:
- Crohn's disease is a chronic inflammatory bowel disease with a typically later age of onset.
- The incidence of Crohn's disease in pediatric populations, particularly in Korea, is notably low.
- Intractable abdominal pain, diarrhea, and fever are common presenting symptoms in pediatric inflammatory bowel disease.
Abstract:
A case of rather typical Crohn's disease in a 10 year old girl is described. She had suffered from intractable abdominal pain, diarrhea and fever for 1 year. Eventual right hemicolectomy revealed diffuse involvement of terminal ileum, cecum and ascending colon by confluent ulcerations and transmural inflammation. Histologically there were numerous well developed non-caseating granulomas scattered transmurally and in regional lymph nodes. Deep penetrating ulcerations were characteristic. Acid fast staining failed to demonstrate any organism. The rarity of Crohn's disease in Korea and this occurrence in pediatric age prompted this report.