Related Experiment Videos
The structure and absolute configuration of acetomycin
F H Cano1, C Foces-Foces, J Elguero
1UEI Cristalografia, Instituto de Quimica-Fisica Rocasolano, CSIC, Madrid, Spain.
Summary
This study determined the absolute configuration of a compound with molecular formula C10H14O5. The crystal structure reveals a five-membered ring with substituents in cis positions, consistent with related derivatives.
Area of Science:
- Crystallography
- Organic Chemistry
- Structural Chemistry
Background:
- Crystallographic data provides essential information about molecular structure and properties.
- Determining absolute configuration is crucial for understanding stereochemistry and biological activity.
Purpose of the Study:
- To elucidate the crystal structure and determine the absolute configuration of C10H14O5.
- To compare the determined structural parameters with those of a bromoacetoxy derivative.
Main Methods:
- Single-crystal X-ray diffraction was employed to analyze the compound.
- The crystal system was identified as orthorhombic with space group P2(1)2(1)2(1).
- Absolute configuration was determined using observed Friedel pairs.
Main Results:
- The molecular formula is C10H14O5, with a molecular weight of 214.22 g/mol.
- The crystal structure exhibits an envelope conformation for the five-membered ring.
- The absolute configuration was determined as 3S, 4R, 5R, with bulky substituents in cis positions.
Conclusions:
- The determined absolute configuration and structural features are consistent with the bromoacetoxy derivative.
- This research contributes to the understanding of stereochemistry in organic molecules.