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Drugs administered through various routes can lead to nonlinear elimination, resulting in complex pharmacokinetic behaviors crucial to understanding efficacious drug dosing.
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A pruning feedforward small-world neural network based on Katz centrality for nonlinear system modeling.

Wenjing Li1, Minghui Chu1, Junfei Qiao1

  • 1Faculty of Information Technology, Beijing University of Technology, Beijing, 100124, China; Beijing Key Laboratory of Computational Intelligence and Intelligent System, Beijing, 100124, China; Beijing Advanced Innovation Center for Future Internet Technology, Beijing, 100124, China.

Neural Networks : the Official Journal of the International Neural Network Society
|July 26, 2020
PubMed
Summary

This study introduces a pruning feedforward small-world neural network (PFSWNN) for nonlinear system modeling. The novel PFSWNN improves generalization performance and reduces training time through an efficient pruning algorithm.

Keywords:
Katz centralityNonlinear system modelingPruning algorithmSmall-world neural network

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Area of Science:

  • Artificial Intelligence
  • Computational Neuroscience
  • Machine Learning

Background:

  • Small-world neural networks enhance artificial neural network generalization but often feature large, predefined architectures.
  • Large architectures can lead to overfitting and prolonged training times, hindering optimal structure discovery.

Purpose of the Study:

  • To propose a pruning feedforward small-world neural network (PFSWNN) for efficient nonlinear system modeling.
  • To address limitations of traditional small-world networks, including overfitting and computational cost.

Main Methods:

  • Constructed a feedforward small-world neural network (FSWNN) using the Watts-Strogatz rewiring rule.
  • Implemented a pruning strategy based on Katz centrality to identify and merge unimportant hidden neurons.
  • Trained connection weights via gradient-based algorithms and theoretically analyzed PFSWNN convergence.

Main Results:

  • PFSWNN demonstrated superior generalization performance on diverse nonlinear system modeling tasks.
  • The pruning algorithm resulted in a compact network structure, significantly shortening training time.
  • Effectiveness validated on function approximation, time-series prediction, benchmark datasets, and wastewater treatment processes.

Conclusions:

  • The proposed PFSWNN effectively combines small-world properties with a pruning mechanism for enhanced performance.
  • PFSWNN offers an automated approach to discovering optimal network structures, overcoming limitations of predefined architectures.
  • This method provides a computationally efficient and high-performing solution for complex nonlinear system modeling.