Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

NNDock2: A neural network-based scoring function for ranking protein-protein docking models.

Journal of bioinformatics and computational biology·2026
Same author

Metal-organic frameworks-coated stainless-steel needles for solid-phase microextraction of phthalates.

Mikrochimica acta·2026
Same author

Explainable AI-SERS approach for highly accurate discrimination of <i>Escherichia coli</i> pathotypes and <i>Shigella</i> species.

Current research in microbial sciences·2026
Same author

Effects of sialylated oligosaccharides on the N- and O-glycosylation of etanercept in recombinant CHO cells.

Applied microbiology and biotechnology·2026
Same author

Improvement of protein purity in etanercept production through process optimization in recombinant CHO cell-based transient gene expression system.

Bioprocess and biosystems engineering·2026
Same author

Herbal plant licorice (<i>Glycyrrhiza glabra</i>) root-activated carbon-based material for methyl violet and crystal violet dyes removal: thermochemical synthesis and experimental design optimization.

International journal of phytoremediation·2026

Related Experiment Video

Updated: Dec 13, 2025

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants
08:13

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants

Published on: February 19, 2016

9.6K

Surface-enhanced Raman scattering-active AuNR array cellulose films for multi-hazard detection.

Dabum Kim1, Goomin Gwon1, Gangyoon Lee1

  • 1Department of Plant & Environmental New Resources, Graduate School of Biotechnology, Kyung Hee University, 1732 Deogyeong-daero, Giheung-gu, Yongin-si, Gyeonggi-do, 446-701, South Korea.

Journal of Hazardous Materials
|July 26, 2020
PubMed
Summary

We developed a novel surface-enhanced Raman scattering (SERS)-active array film using cellulose hydrogels and gold nanorods. This flexible film enables simultaneous detection of multiple analytes with high sensitivity.

Keywords:
ArrayHazardous chemicalsPlasmonic nanostructureRegenerated cellulose hydrogelSERS

More Related Videos

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

21.0K
Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs
03:33

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs

Published on: November 17, 2023

3.0K

Related Experiment Videos

Last Updated: Dec 13, 2025

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants
08:13

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants

Published on: February 19, 2016

9.6K
Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

21.0K
Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs
03:33

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs

Published on: November 17, 2023

3.0K

Area of Science:

  • Materials Science
  • Nanotechnology
  • Spectroscopy

Background:

  • Surface-enhanced Raman scattering (SERS) is a powerful technique for trace molecule detection.
  • Developing sensitive and reproducible SERS substrates is crucial for practical applications.
  • Existing SERS substrates often lack flexibility and multi-analyte detection capabilities.

Purpose of the Study:

  • To create a flexible, SERS-active array film for simultaneous multi-analyte detection.
  • To investigate the role of hydrogel structure and nanorod spacing on SERS enhancement.
  • To evaluate the sensitivity, reproducibility, and stability of the developed SERS sensor.

Main Methods:

  • Fabrication of a SERS-active array film using regenerated cellulose hydrogels and gold nanorods (AuNRs).
  • Utilized a silicon rubber mask and vacuum filtration for controlled AuNR array formation.
  • Manipulated hydrogel deformation to control interparticle nanogaps for enhanced SERS.
  • Tested SERS sensor arrays for detecting rhodamine 6G and thiram at low concentrations.

Main Results:

  • Achieved precise control over AuNR number density and interparticle nanogaps.
  • Demonstrated excellent SERS activity with high enhancement factors (up to 9.5 × 10^9).
  • Detected rhodamine 6G and thiram at picomolar (pM) and femtomolar (fM) levels, respectively.
  • Successfully detected nine different analytes simultaneously on a single substrate.
  • Showcased high reproducibility and minimal SERS activity change upon physical bending.

Conclusions:

  • The developed cellulose hydrogel-based AuNR array film is a highly sensitive and reproducible SERS substrate.
  • The flexible nature and multi-analyte detection capability offer significant potential for practical SERS analysis.
  • This platform is promising for simultaneous detection of multiple hazards in various applications.