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A Protocol for Analyzing Hepatitis C Virus Replication
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Screening for Hepatitis C Virus: How Universal Is Universal?

Ravi Jhaveri1

  • 1Division of Pediatric Infectious Diseases, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Box 20, Chicago, IL, USA.

Clinical Therapeutics
|July 27, 2020
PubMed
Summary

Updated hepatitis C virus (HCV) screening now recommends all adults get tested. While universal, this commentary examines if all high-risk populations are fully covered by the new guidelines.

Keywords:
baby boomershepatitis C virusinjection drug usepregnant womenscreeningyoung adults

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Area of Science:

  • Public Health
  • Infectious Diseases
  • Hepatology

Background:

  • Hepatitis C virus (HCV) infection rates have increased, particularly among those who inject drugs.
  • Highly effective curative therapies for HCV are now available.
  • Recent updates in March and April 2020 revised public health screening recommendations.

Purpose of the Study:

  • To review the details of the updated hepatitis C virus screening recommendations.
  • To discuss high-risk populations potentially not fully addressed by the universal screening guidelines.

Main Methods:

  • Review of updated public health screening guidelines for hepatitis C virus.
  • Analysis of the scope and limitations of the "universal" screening recommendation.

Main Results:

  • The updated recommendation advises one-time hepatitis C virus antibody screening for all adults aged 18 years and older.
  • The "universal" nature of the recommendation may not adequately capture all individuals within high-risk groups.

Conclusions:

  • The new universal hepatitis C virus screening guidelines represent a significant public health advancement.
  • Further consideration is needed to ensure comprehensive screening for all at-risk populations.