Relationships between resting blood flow and the indices of muscle damage after eccentric contractions

The aim of the study is to examine the relationships between increments in resting blood flow and isometric maximal voluntary contraction (MVC) force reduction, muscle soreness, and swelling after eccentric contractions (ECs).

Twenty-one young healthy men (age 20.8 ± 1.6 years; height 172.0 ± 5.3 cm; weight 64.9 ± 7.7 kg) were recruited for this study. All participants performed right arm ECs in five sets of 20 repetitions with 3 min of rest between the sets. The dumbbell weight corresponded to 60% MVC force of isometric contraction of elbow flexors with 90° elbow joint angle. Resting forearm blood flow (FBF), the MVC force, the muscle thickness (MT), and muscle soreness of elbow flexors, heart rate (HR), and blood pressure (BP) of brachial artery were measured before, 24 and 48 h after ECs.

Average and peak resting FBF after ECs significantly changed from the average values before ECs (21% and 39% increase, respectively, P < 0.01). However, resting HR and BP were not significantly different after ECs. Average increase in resting FBF showed a significant relationship with average isometric MVC force reduction (r =  - 0.45, P < 0.05), peak isometric MVC force reduction (r =  - 0.48, P < 0.05), average muscle soreness (r = 0.49, P < 0.05), and peak muscle soreness (r = 0.49, P < 0.05). Moreover, stepwise multiple regression analysis revealed that average increased resting FBF was explained by isometric MVC force reduction and muscle soreness (adjusted R² = 0.33).

These results suggested that increments in resting blood flow reflect muscle damage, and increased resting blood flow may be a result of acute inflammatory response induced by muscle damage.