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Related Experiment Video

Updated: Dec 13, 2025

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Meniscal substitution, a developing and long-awaited demand.

Philipp W Winkler1,2, Benjamin B Rothrauff1,3, Rafael A Buerba1

  • 1Department of Orthopaedic Surgery, UPMC Freddie Fu Sports Medicine Center, University of Pittsburgh, 3200 S. Water St, Pittsburgh, PA, 15203, USA.

Journal of Experimental Orthopaedics
|July 27, 2020
PubMed
Summary
This summary is machine-generated.

Meniscal injuries often require surgical intervention. This article reviews available meniscus substitutes, including autologous, allogenic, and artificial options, to preserve knee function.

Keywords:
AllograftKneeMeniscusScaffoldSubstituteTissue engineeringTransplantation

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Area of Science:

  • Orthopedic surgery
  • Biomedical engineering
  • Sports medicine

Background:

  • Menisci are crucial for knee joint function.
  • Meniscal injuries result from sports, trauma, or degeneration.
  • Meniscus preservation is preferred, but resection is sometimes necessary.

Purpose of the Study:

  • To review current meniscal substitution techniques.
  • To discuss anatomical and biomechanical aspects of substitutes.
  • To evaluate clinical outcomes and future directions for meniscal repair.

Main Methods:

  • Review of anatomical and biomechanical knowledge.
  • Analysis of clinical applications of meniscal substitutes.
  • Evaluation of radiological and clinical outcomes.
  • Discussion of future perspectives in meniscal substitution.

Main Results:

  • Various meniscal substitutes (autologous, allogenic, artificial) have evolved.
  • These substitutes aim to restore knee function after meniscal loss.
  • Clinical and radiological outcomes vary among different substitute types.

Conclusions:

  • Meniscal substitution is essential when resection is unavoidable.
  • Understanding different meniscal substitute options is vital for clinical practice.
  • Integrating evolving meniscal substitution techniques can prevent long-term knee dysfunction.