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Hemorrhage Rates in Pediatric Patients Receiving Postoperative Steroids After Tonsillectomy
Bryce Randall Noblitt1, Fariha Siddiqui1, Kenneth C Iverson1
1University of Kentucky, Lexington, KY, USA.
Insights
Postoperative steroid use after tonsillectomy in children does not increase the risk of bleeding requiring surgery. This study found similar hemorrhage rates in children who received steroids versus those who did not.
Area of Science:
- Pediatric Otolaryngology
- Pharmacology
- Surgical Outcomes
Background:
- Effective pain management after tonsillectomy is crucial for pediatric patients.
- Postoperative steroids may offer pain relief, but their impact on bleeding risk is unclear.
- Tonsillectomy is a common pediatric surgical procedure with potential complications like hemorrhage.
Purpose of the Study:
- To investigate the association between postoperative steroid administration and the risk of hemorrhage after pediatric tonsillectomy.
- To determine if steroid use increases the need for surgical intervention due to bleeding post-tonsillectomy.
- To evaluate the safety of using steroids for pain management in pediatric tonsillectomy patients.
Main Methods:
- Retrospective cohort study design.
- Inclusion of age- and indication-matched pediatric patients (≤12 years) undergoing tonsillectomy between 2012 and 2017.
- Comparison of postoperative hemorrhage rates requiring operative intervention between patients receiving prednisolone and those not receiving steroids.
Main Results:
- A total of 1358 pediatric patients were analyzed.
- The rate of operative intervention for post-tonsillectomy hemorrhage was 1.8% in the steroid group and 2.2% in the non-steroid group.
- No statistically significant difference in hemorrhage rates was observed between the two groups (P = .560).
Conclusions:
- Postoperative steroid use in children following tonsillectomy is not associated with an increased risk of hemorrhage requiring operative intervention.
- Steroids can be considered a safe option for pain management after pediatric tonsillectomy regarding bleeding risk.
- Further research may explore optimal steroid dosing and long-term outcomes.
Abstract:
Importance. Developing a safe postoperative pain regimen after tonsillectomy is important. While postoperative steroids may provide an analgesic benefit, it is not known whether steroids increase the bleeding risk after tonsillectomy. Objective. To determine whether postoperative steroids increase the risk of hemorrhage after tonsillectomy in children. Design. Retrospective cohort study. Setting. Tertiary referral academic medical center. Participants. An age- and indication-matched cohort was randomly selected from tonsillectomy patients ≤12 years old from 2012 to 2017. Intervention. Prednisolone, 0.5 mg/kg (maximum dose 20 mg/day) qAM × 3 days postoperatively. Main Outcome. Postoperative hemorrhage requiring operative intervention. Results. A total of 1358 patients were included in this study, 679 of which received postoperative steroids. The steroid group had a similar of operative intervention for post-tonsillectomy hemorrhage of 1.8% versus 2.2% in the nonsteroid group (P = .560). Conclusion and Relevance. Post-tonsillectomy steroid use is not associated with an increase in operative intervention for postoperative hemorrhage.
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