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Updated: Dec 13, 2025

Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers
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Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers

Published on: September 19, 2022

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Cell-penetrating and mitochondrion-targeting molecules

George Appiah Kubi1, Dehua Pei1

  • 1Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, United States.

Methods in Enzymology
|July 28, 2020
PubMed
Summary

Researchers developed novel cell-penetrating molecules (CPMs) for targeted delivery into mitochondria. These CPMs successfully deliver therapeutic cargos into the mitochondrial matrix, overcoming previous delivery challenges.

Keywords:
Cell-penetrating moleculeCyclic peptideDrug deliveryMitochondrion targetingPeptide

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