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A Protocol for the Administration of Real-Time fMRI Neurofeedback Training
Published on: August 24, 2017
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Neurofeedback self-regulating training in patients with Post traumatic stress disorder: A randomized controlled trial
Jungtae Leem1,2, Moon Joo Cheong3, Sang-Hoon Yoon2
1Research and Development Institute, CY Pharma Co., Seoul, South Korea.
Integrative Medicine Research
|July 28, 2020
Summary
This study investigates neurofeedback using quantitative electroencephalography (EEG) to treat post-traumatic stress disorder (PTSD). It aims to provide evidence for neurofeedback as an effective, integrative treatment for PTSD patients.
Area of Science:
- Neuroscience
- Clinical Psychology
- Biomedical Engineering
Background:
- Post-traumatic stress disorder (PTSD) presents a significant public health challenge with limitations in current treatments.
- Neurofeedback, utilizing electroencephalography (EEG) to monitor physiological functions, is explored as a therapeutic option for PTSD.
Purpose of the Study:
- To assess the efficacy and safety of neurofeedback treatment in patients diagnosed with PTSD.
- To utilize quantitative EEG to monitor brain wave activity and physiological functions during treatment.
Main Methods:
- A randomized, waitlist-controlled, assessor-blinded clinical trial involving 46 PTSD patients.
- Participants receive 16 sessions of neurofeedback over 8 weeks, with quantitative EEG monitoring.
- Primary outcome measured by the Korean version of PTSD Checklist-5 (PCL-5-K) scores at week 8.
Main Results:
- The study is designed to compare PCL-5-K scores between the neurofeedback and control groups at week 8.
- Secondary outcomes include assessments of anxiety, depression, insomnia, emotions, EEG patterns, quality of life, and safety.
- A four-week follow-up period will assess sustained effects.
Conclusions:
- The trial will detail a methodology for applying neurofeedback with quantitative EEG in PTSD treatment.
- Results are expected to offer insights into an integrative therapeutic strategy for PTSD management.
- This research aims to provide foundational evidence for neurofeedback's role in treating PTSD.

