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Updated: Dec 13, 2025

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
Soft tissue coverage options around the knee
N Kerfant1, P Ta1, A Trimaille1
1Department of Plastic and Reconstructive Surgery, Brest University Hospital, boulevard Tanguy-Prigent, 29609 Brest cedex, France.
Abstract:
Defects around the knee exhibit various etiologies and pose challenges to both orthopedists and plastic surgeons. While a number of reconstructive coverage options are available, flaps are almost always required for complex defects. Many local flaps are easily placed, including muscle and perforator flaps sourced from the thigh to the leg. As the recipient vessels lie deep, free tissue transfers are challenging. Good postoperative management and efficient collaboration between orthopedic and reconstructive surgeons are the keys to successful knee reconstruction, restoring an esthetic contour and preserving joint function.
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