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Updated: Dec 13, 2025

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Neuroeconomics for the study of social cognition in adolescent depression
William Mellick1, Carla Sharp1, Monique Ernst2
1University of Houston, Department of Psychology, University of Houston, 126 Heyne Building, Houston, TX 77204, United States.
Abstract:
Traditional social-cognitive approaches for investigating interpersonal problems in adolescent depression are limited. An important functional domain studied in adolescent depression is reward, but experimental paradigms have largely been non-social. In this paper, we propose the methods and concepts of neuroeconomics may address this gap. We begin by discussing a well-established social reward model for vulnerability to adolescent depression. We then show how neuroeconomics may extend this model by offering the tools to examine the mechanics of social exchanges, in behavioral and neural terms, that maintain (or pose vulnerability to) depression. In doing so, we propose a neureoconomic model of adolescent depression in which depression is defined as a perturbation of interpersonal motivational/reward exchange. This model serves to guide future research.
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