Enterococci, from Harmless Bacteria to a Pathogen
Sónia Ramos1,2,3, Vanessa Silva1,2,3,4, Maria de Lurdes Enes Dapkevicius5,6
1Microbiology and Antibiotic Resistance Team (MicroART), Department of Veterinary Sciences, University of Trás-os-Montes and Alto Douro (UTAD), 5001-801 Vila Real, Portugal.
Microorganisms
|July 30, 2020
Summary
Enterococci bacteria are becoming resistant to antibiotics, posing a significant public health threat. Enhanced surveillance and antibiotic stewardship are crucial to combat this growing challenge.
Area of Science:
- Microbiology
- Infectious Diseases
- Public Health
Background:
- Enterococci are common gut bacteria with remarkable hardiness.
- Their adaptability allows colonization of diverse environments, including hospitals.
- Genome plasticity facilitates rapid acquisition and spread of antibiotic resistance.
Purpose of the Study:
- To review the emergence and dissemination of enterococcal antibiotic resistance.
- To highlight the public health significance of this resistance.
- To advocate for improved surveillance and antibiotic stewardship.
Main Methods:
- Literature review of enterococcal antibiotic resistance.
- Analysis of resistance mechanisms and dissemination pathways.
- Assessment of public health implications.
Main Results:
- Enterococci exhibit resistance to key antimicrobial agents.
- Dissemination of resistance determinants is widespread.
- This resistance poses a major clinical and public health problem.
Conclusions:
- Enterococcal antibiotic resistance is a growing concern.
- Effective surveillance programs are needed.
- Enhanced antibiotic stewardship is essential to mitigate risks.
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