HDR UK supporting mobilising computable biomedical knowledge in the UK

Area of Science:

• Health Informatics
• Biomedical Research
• Data Science

Background:

• Computable biomedical knowledge (CBK) is a rapidly advancing field with significant potential for improving patient outcomes.
• Health Data Research UK (HDR UK) is the national Institute for Health Data Science, dedicated to integrating UK health data for research and discovery.
• HDR UK comprises the UK HDR Alliance, HDR Hubs, and the HDR Innovation Gateway to facilitate data access and interoperability.

Purpose of the Study:

• To outline the structure and initiatives of Health Data Research UK (HDR UK) in advancing computable biomedical knowledge (CBK).
• To highlight HDR UK's commitment to open data standards, international collaboration, and the development of a national phenomics platform.
• To emphasize the role of HDR UK in enabling safe data use, building public trust, and fostering innovation in health data science.

Main Methods:

• Establishing a national alliance of data custodians committed to safe data sharing.
• Developing HDR Hubs as centers of expertise for data curation and domain-specific services.
• Implementing the HDR Innovation Gateway for data discovery, accessibility, security, and interoperability.

Main Results:

• Encouraging the adoption of open data standards for research purposes.
• Fostering collaboration with the international CBK community for evaluation and joint initiatives.
• Creating a national platform for disseminating machine-readable phenotypical algorithms through a dedicated phenomics workstream.

Conclusions:

• HDR UK's integrated approach supports the development and application of computable biomedical knowledge.
• The initiatives aim to reduce duplication of effort and enhance the reproducibility of clinical studies.
• HDR UK is pivotal in leveraging health data for translational research and improving public health.