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Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS
Published on: November 8, 2015
Ointment tacrolimus for steroid resistant adenoviral nummular keratitis
M Jamaluddin Ahmad1, P W Lott2, N Khaliddin2
1University Malaya Medical Centre, Department of Ophthalmology, Kuala Lumpur, Malaysia. marium87mja@gmail.com.
Abstract:
A 33-year-old man presented with a four-day history of redness and blurring of vision of the right eye. A clinical diagnosis of adenoviral keratitis was made with a differential of microsporidia epithelial keratitis. The patient subsequently developed nummular keratitis which was resistant to topical steroids. He continued to develop multiple recurrences of the condition. Treatment with tacrolimus ointment was started as the patient had an elevated intraocular pressure due to prolonged steroid use. Tacrolimus ointment showed a favourable outcome in the management of recurrent nummular keratitis.
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