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Multidrug-Resistant Burkholderia cepacia, Candida dubliniensis, and Candida glabrata Infected Pancreatic Pseudocyst
Sarah Rawi1, Bryan Stringer1, Myrla Sajo2
1Internal Medicine, University of Connecticut Health Center, Farmington, USA.
Abstract:
Burkholderia cepacia is a gram-negative bacillus that is most commonly associated with pneumonia in the immunocompromised patients. The most common organisms associated with pancreatic infections are Escherichia coli, Klebsiella pneumoniae, Enterobacter spp., and Enterococcus spp. We report a case of a 45-year-old gentleman with recent acute pancreatitis who presented with hypoglycemia, altered mental status, worsening epigastric pain, and early satiety. He was diagnosed with a large peripancreatic infected cyst which grew multidrug-resistant (MDR) Burkholderia cepacia, Candida glabrata, and Candida dubliniensis. This case report focuses on the importance of distinguishing and recognizing risk factors for this MDR organism, in order to provide better patient care.
Insights
A rare case of multidrug-resistant Burkholderia cepacia caused a pancreatic infection in an immunocompromised patient. Early recognition of risk factors is crucial for managing this challenging infection.
Area of Science:
- Infectious Diseases
- Microbiology
- Gastroenterology
Background:
- Burkholderia cepacia is typically linked to pneumonia in immunocompromised individuals.
- Common pancreatic infection culprits include E. coli, K. pneumoniae, Enterobacter, and Enterococcus species.
Observation:
- A 45-year-old male with acute pancreatitis developed hypoglycemia, altered mental status, and severe epigastric pain.
- Imaging revealed a large peripancreatic infected cyst.
Findings:
- The infected cyst yielded multidrug-resistant (MDR) Burkholderia cepacia, Candida glabrata, and Candida dubliniensis.
- This represents an unusual polymicrobial infection involving an MDR organism in pancreatic pathology.
Implications:
- Highlights the need to consider unusual pathogens in pancreatic infections, especially in immunocompromised patients.
- Emphasizes the importance of identifying risk factors for MDR organisms like B. cepacia for improved patient outcomes.
- Underscores the necessity for prompt and accurate microbiological diagnosis in complex intra-abdominal infections.
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