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COVID-19 cardiovascular epidemiology, cellular pathogenesis, clinical manifestations and management

Yasar Sattar1, Waqas Ullah2, Hiba Rauf3

  • 1Internal Medicine, Icahn School of Medicine at Mount Sinai - Elmhurst Hospital, NY, USA.

International Journal of Cardiology. Heart & Vasculature
|July 30, 2020
PubMed

Insights

Coronavirus Disease 2019 (COVID-19) causes various cardiac issues, especially in those with prior heart conditions. This review covers COVID-19

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Pathophysiology

Background:

  • Coronavirus Disease 2019 (COVID-19) is a global pandemic.
  • Cardiovascular manifestations are common in COVID-19 patients.
  • Pre-existing cardiac conditions exacerbate COVID-19's cardiac effects.

Purpose of the Study:

  • To review the cellular pathophysiology of cardiac manifestations in COVID-19.
  • To outline the clinical presentations of cardiac involvement in COVID-19.
  • To discuss treatment strategies for COVID-19-related cardiac conditions.

Main Methods:

  • Literature review of cellular pathophysiology.
  • Analysis of clinical manifestations.
  • Summary of current treatment modalities.

Main Results:

  • COVID-19 can lead to myocardial injury, infarction, arrhythmias, heart failure, cardiomyopathy, shock, thromboembolism, and cardiac arrest.
  • Patients with coronary artery disease, hypertension, diabetes, and coagulation disorders face worse outcomes.
  • Advanced age and immunocompromised states are significant risk factors.

Conclusions:

  • Understanding the pathophysiology is crucial for managing cardiac complications.
  • Early recognition and tailored treatment are essential for improving patient outcomes.
  • Multidisciplinary approaches are needed to address the complex cardiac sequelae of COVID-19.

Keywords:
COVID-19CardiovascularComplications, and treatmentCoronavirus disease 2019PathophysiologySARS-CoV-2

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