Blood routine test in mild and common 2019 coronavirus (COVID-19) patients

Dodji Kossi Djakpo1, Zhiquan Wang1, Rong Zhang2

  • 1Department of Cardiology, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei, China.

Bioscience Reports
|July 30, 2020
PubMed

Insights

Complete blood count (CBC) analysis in mild COVID-19 patients reveals significant changes in red blood cells, hemoglobin, hematocrit, and C-reactive protein levels. These findings offer valuable insights for clinicians managing patients with coronavirus disease 2019.

Area of Science:

  • Hematology
  • Infectious Diseases
  • Virology

Background:

  • The 2019 coronavirus disease (COVID-19) has been declared a pandemic by the WHO.
  • Understanding the hematological manifestations of COVID-19 is crucial for clinical management.
  • Complete blood count (CBC) is a fundamental diagnostic tool.

Purpose of the Study:

  • To report the complete blood count (CBC) findings in patients with mild COVID-19.
  • To provide physicians with expected CBC changes in mild coronavirus disease 2019 cases.
  • To identify significant hematological alterations associated with COVID-19.

Main Methods:

  • Retrospective analysis of CBC data from 208 mild COVID-19 patients.
  • Patients were admitted to Dongnan Hospital in Xiaogan, Hubei, China.
  • Statistical analysis was performed using IBM SPSS, with significance set at P<0.05.

Main Results:

  • Significant changes were observed in red blood cell (RBC) levels.
  • Alterations in hemoglobin (HGB) and hematocrit (HCT) were noted.
  • Mean corpuscular volume (MCV) and C-reactive protein (CRP) levels also showed significant changes.

Conclusions:

  • CBC analysis reveals distinct hematological changes in mild COVID-19 patients.
  • Clinicians should be aware of these CBC findings when diagnosing and managing coronavirus disease 2019.
  • These findings contribute to the understanding of COVID-19's impact on blood parameters.

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