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Updated: Dec 13, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
Blood routine test in mild and common 2019 coronavirus (COVID-19) patients
Dodji Kossi Djakpo1, Zhiquan Wang1, Rong Zhang2
1Department of Cardiology, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei, China.
Insights
Complete blood count (CBC) analysis in mild COVID-19 patients reveals significant changes in red blood cells, hemoglobin, hematocrit, and C-reactive protein levels. These findings offer valuable insights for clinicians managing patients with coronavirus disease 2019.
Area of Science:
- Hematology
- Infectious Diseases
- Virology
Background:
- The 2019 coronavirus disease (COVID-19) has been declared a pandemic by the WHO.
- Understanding the hematological manifestations of COVID-19 is crucial for clinical management.
- Complete blood count (CBC) is a fundamental diagnostic tool.
Purpose of the Study:
- To report the complete blood count (CBC) findings in patients with mild COVID-19.
- To provide physicians with expected CBC changes in mild coronavirus disease 2019 cases.
- To identify significant hematological alterations associated with COVID-19.
Main Methods:
- Retrospective analysis of CBC data from 208 mild COVID-19 patients.
- Patients were admitted to Dongnan Hospital in Xiaogan, Hubei, China.
- Statistical analysis was performed using IBM SPSS, with significance set at P<0.05.
Main Results:
- Significant changes were observed in red blood cell (RBC) levels.
- Alterations in hemoglobin (HGB) and hematocrit (HCT) were noted.
- Mean corpuscular volume (MCV) and C-reactive protein (CRP) levels also showed significant changes.
Conclusions:
- CBC analysis reveals distinct hematological changes in mild COVID-19 patients.
- Clinicians should be aware of these CBC findings when diagnosing and managing coronavirus disease 2019.
- These findings contribute to the understanding of COVID-19's impact on blood parameters.
Abstract:
The new 2019 coronavirus disease (COVID-19), according to the World Health Organization (WHO), has been characterized as a pandemic. As more is being discovered about this virus, we aim to report findings of the complete blood count (CBC) of COVID-19 patients. This would serve in providing physicians with important knowledge on the changes that can be expected from the CBC of mild and normal COVID-19 patients. A total of 208 mild and common patients were admitted at the Dongnan Hospital located in the city of Xiaogan, Hubei, China. The CBCs of these patients, following a confirmed diagnosis of COVID-19, were retrospectively analyzed and a significant P<0.05 was found after a full statistical analysis was conducted using the Statistical Package for the Social Sciences (IBM SPSS). CBC analysis revealed changes in the levels of red blood cells (RBCs), hemoglobin (HGB), hematocrit (HCT), mean corpuscular volume (MCV), and C-reactive protein (CRP). Clinicians should expect similar findings when dealing with the new COVID-19.
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