Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Intellectual Disability01:29

Intellectual Disability

428
Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
428
Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

1.5K
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
1.5K
Learning Disabilities01:25

Learning Disabilities

487
Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
Dyslexia
Dyslexia is a...
487

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Safe and Early Primary Closure of Open Abdomen in Pediatric Liver Transplantation Using a Doppler-Guided Tension Relief Strategy and Enhanced Wound Environment.

Journal of transplantation·2026
Same author

Human biliary atresia extrahepatic cholangiocyte organoids express increased ER and oxidative stress, altered drug metabolism and cell polarity changes.

Frontiers in bioengineering and biotechnology·2026
Same author

A plain language summary on clinical and mechanistic effects of cladribine in relapsing multiple sclerosis: 2-year results from the MAGNIFY-MS study.

Neurodegenerative disease management·2026
Same author

Excellent Outcome of Residual Pulmonary Metastases in Initially High Burden Metastatic Hepatoblastoma: A Case Series.

Journal of pediatric hematology/oncology·2026
Same author

Laparoscopic Living Donor Nephrectomy: Learning Curve Analysis Through 1446 Cases and Outcomes from 200 Consecutive Mastery-Phase Procedures-How I Do It.

Journal of clinical medicine·2026
Same author

Neurofilament Light Chain Measurements by Centaur and Simoa Systems in Human and Murine Samples.

The Israel Medical Association journal : IMAJ·2026

Related Experiment Video

Updated: Dec 13, 2025

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.5K

Parity and disability progression in relapsing-remitting multiple sclerosis.

Anat Achiron1, Alon Ben-David2, Michael Gurevich3

  • 1Multiple Sclerosis Center, Sheba Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel. anat.achiron@sheba.health.gov.il.

Journal of Neurology
|July 30, 2020
PubMed
Summary

Childbirth after multiple sclerosis onset may reduce the risk of moderate neurological disability. Increasing parity did not further impact disability progression, and treatments showed no effect in a subgroup analysis.

Keywords:
Disability progressionImmunomodulatory treatmentParityPregnancyRelapsing–remitting multiple sclerosis

More Related Videos

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

10.9K
Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis
08:11

Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis

Published on: November 14, 2016

11.4K

Related Experiment Videos

Last Updated: Dec 13, 2025

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.5K
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

10.9K
Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis
08:11

Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis

Published on: November 14, 2016

11.4K

Area of Science:

  • Neurology
  • Reproductive Health

Background:

  • Parity's role in multiple sclerosis (MS) disability progression remains unclear.
  • Limited data exist on immunomodulatory treatments' effects in parous MS patients.

Purpose of the Study:

  • To investigate the association between parity and long-term neurological disability in relapsing-remitting MS (RRMS).
  • To evaluate the impact of childbirth timing on disability progression in women with RRMS.

Main Methods:

  • A cohort study analyzed 2281 women with RRMS in Israel (1995-2018).
  • Cox regression models assessed disability progression risk related to parity, using childbirth as a time-dependent covariate.

Main Results:

  • Parity was linked to a reduced risk of moderate disability (adj.HR, 0.68; P=0.001) but not severe disability.
  • No significant difference in progression risk was observed for one, two, or three+ births.
  • Immunomodulatory treatment did not influence disability-free survival in women giving birth within 5 years of MS onset.

Conclusions:

  • Childbirth following MS onset is associated with decreased risk of moderate neurological disability.
  • Parity does not appear to be a significant risk factor for severe disability progression in RRMS.