NMDAR-Dependent Emergence of Behavioral Representation in Primary Visual Cortex

Alicja Puścian1, Hadas Benisty2, Michael J Higley2

  • 1Department of Neuroscience, Kavli Institute of Neuroscience, Yale University School of Medicine, New Haven, CT 06510, USA; Nencki-EMBL Partnership for Neural Plasticity and Brain Disorders - BRAINCITY, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Pasteur 3 Street, 02-093 Warsaw, Poland.

Cell Reports
|July 30, 2020
PubMed
Summary

Primary visual cortex (V1) neurons develop accurate behavioral representations during learning, not inherent to V1. This plasticity requires NMDA-type glutamate receptors for visual task performance.

Related Concept Videos

Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
6.3K
Vision01:24

Vision

Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
59.0K
Association Areas of the Cortex01:21

Association Areas of the Cortex

Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
8.3K
Visual System01:26

Visual System

Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
1.5K