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Related Concept Videos

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IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
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IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
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Related Experiment Video

Updated: Dec 13, 2025

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
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Initial experience with the Perceval S sutureless aortic valve.

Tatjana Raickovic1, Igor Zivkovic1, Tatjana Ragus1

  • 1Department of Cardiac Surgery, Dedinje Cardiovascular Institute, Belgrade, Serbia.

Kardiochirurgia I Torakochirurgia Polska = Polish Journal of Cardio-Thoracic Surgery
|July 31, 2020
PubMed
Summary

Sutureless aortic valve replacement using the Perceval S bioprosthesis is safe and shows favorable early hemodynamic performance. This approach may reduce procedure times, benefiting high-risk patients and facilitating minimally invasive surgery.

Keywords:
Perceval S bioprosthesisaortic valve replacementsutureless valve

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Area of Science:

  • Cardiovascular Surgery
  • Bioprosthetic Valves
  • Minimally Invasive Cardiac Surgery

Background:

  • Aortic valve replacement (AVR) is a common cardiac operation.
  • Surgical treatment of the aortic valve remains the gold standard.

Purpose of the Study:

  • To evaluate the early outcomes of aortic valve replacement (AVR) using the Perceval S sutureless bioprosthesis.

Main Methods:

  • Retrospective analysis of 24 patients undergoing AVR with the Perceval S valve.
  • Included isolated AVR and AVR with concomitant coronary artery bypass grafting (CABG).
  • Patient evaluation included pre-operative, hospital discharge, and follow-up assessments.

Main Results:

  • No hospital mortality observed.
  • Favorable early hemodynamic performance with low transvalvular pressure gradients.
  • Absence of moderate/severe aortic regurgitation, valve thrombosis, thromboembolic events, or structural deterioration.

Conclusions:

  • Sutureless AVR with Perceval S is safe with favorable early hemodynamics.
  • Reduced cross-clamp and bypass times offer advantages, particularly for high-risk patients.
  • Minimally invasive access is potentially facilitated; further long-term studies are warranted.