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Updated: Dec 13, 2025

Microfluidics in Assessing Platelet Function
Published on: November 8, 2024
Platelet Dysfunction Diseases and Conditions: Clinical Implications and Considerations
Alan D Kaye1, George M Jeha2, Vanessa Moll3
1Department of Anesthesiology, LSU Health Shreveport, Shreveport, LA, USA.
Introduction:
Platelet diseases and dysfunction are taught early in medical school to all future physicians. Understanding of the coagulation cascade and hemostatic mechanisms has allowed for targeted pharmacological therapies that have been significantly impactful in clinical practice. Platelets are an early participant in hemostasis physiologically and under pathophysiological states.
Methods:
A review of literature involving platelet disfunction.
Results:
Various presentations of platelet diseases and dysfunction challenge clinicians and require a firm understanding of normal platelet function, drugs that mediate or modulate platelet effectiveness, and nonpharmacologic etiologies of platelet diseases and dysfunction with corresponding best practice treatment approaches.
Conclusion:
This review summarizes normal and abnormal states associated with platelets and treatment strategies.
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