[Non-functioning pituitary adenomas: epidemiology, clinical and postoperative outcome]

Area of Science:

• Neurosurgery
• Endocrinology
• Ophthalmology

Background:

• Non-functioning pituitary adenomas are common sellar region tumors.
• Often diagnosed due to visual or hormonal symptoms, or incidentally.

Purpose of the Study:

• To analyze clinical features of non-functioning pituitary adenomas.
• To evaluate surgical treatment outcomes and complications.

Main Methods:

• Retrospective analysis of 100 cases.
• Evaluation of epidemiological, clinical, endocrinological, visual, and radiological data.
• Assessment of pre- and post-operative outcomes and long-term follow-up.

Main Results:

• Visual field defects were the most common symptom (62%).
• Hypogonadotropic hypogonadism was the most frequent hormonal deficit (48%).
• Post-surgery, 54.8% had visual field recovery; 4% developed diabetes insipidus. Complete resection (>95%) achieved in 63%.

Conclusions:

• Non-functioning pituitary adenomas respond well to timely surgical intervention.
• Cavernous sinus invasion significantly impacts the feasibility of complete surgical resection.