Calculating degree based multiplicative topological indices of Hyaluronic Acid-Paclitaxel conjugates' molecular structure in cancer treatment
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Micropatterned Surfaces to Study Hyaluronic Acid Interactions with Cancer Cells
Published on: December 22, 2010
Akbar Jahanbani1, Zehui Shao2, Seyed Mahmoud Sheikholeslami1
1Department of Mathematics, Azarbaijan Shahid Madani University, Tabriz, Iran.
Abstract:
A large number of medical experiments have confirmed that the features of drugs have a close correlation with their molecular structure. Drug properties can be obtained by studying the molecular structure of corresponding drugs. The calculation of the topological index of a drug structure enables scientists to have a better understanding of the physical chemistry and biological characteristics of drugs. In this paper, we focus on Hyaluronic Acid-Paclitaxel conjugates which are widely used in the manufacture of anticancer drugs. Several multiplicative topological indices of this molecular structure are determined by using of the edge-partition method.Communicated by Ramaswamy H. Sarma.

