Related Experiment Video
Updated: Dec 13, 2025

Author Spotlight: Developing a Microfluidic Lung-on-Chip Model for In-Depth Study of Human Immune Response and Infection Mechanisms
Published on: May 31, 2024
[Interactive, semi-automatized and open source computational model applied to respiratory viruses surveillance]
Felipe Reyes1, Marcela Ferrés1, Pablo Vial2
1Departamento de Enfermedades Infecciosas e Inmunología Pediátricas, Escuela de Medicina, Pontificia Universidad Católica de Chile, Chile.
A new R and Shiny platform streamlines respiratory virus surveillance, reducing costs and improving data accessibility for public health. This tool enables rapid data upload, analysis, and immediate publication, enhancing response to acute respiratory infections (ARI).
Area of Science:
- Public Health
- Infectious Disease Epidemiology
- Bioinformatics
Background:
- Acute respiratory infections (ARI) pose a significant global health burden, particularly for children and the elderly.
- Effective surveillance of respiratory viruses is crucial for reducing healthcare costs and optimizing public health responses.
- Existing surveillance systems often face challenges with data management, analysis, and timely dissemination.
Purpose of the Study:
- To develop an interactive and user-friendly web platform for the efficient gathering, analysis, and publication of respiratory virus surveillance data.
- To reduce the time and cost associated with data upload and analysis in viral surveillance networks.
- To enhance the accessibility and impact of surveillance data for public health decision-making.
Main Methods:
- Development of a web-based platform utilizing the R programming language and its Shiny package.
- Integration of historical data (since 2006) from the Chilean metropolitan respiratory viruses surveillance network.
- Implementation of features for rapid data upload, interactive analysis, and immediate online publication.
Main Results:
- The platform allows researchers to upload data in under one minute.
- Data analysis and publication are immediate and accessible to internet-connected users.
- The system significantly decreases data processing time and increases the availability and impact of surveillance information.
- The platform was developed with very low cost and in a short timeframe.
Conclusions:
- The developed R and Shiny platform offers a cost-effective and efficient solution for respiratory virus surveillance.
- The interactive and accessible nature of the platform enhances the utility of surveillance data for public health.
- This approach can be instrumental in optimizing health responses to acute respiratory infections globally.
More Related Videos
09:01An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 10, 2013
09:14An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay
Published on: January 26, 2019
Related Concept Videos
Overview of Respiratory System
What is the Respiratory System?
The respiratory system consists of a series of organs responsible for taking in oxygen and expelling carbon dioxide. The primary function of the respiratory system is to...
Assessment of Respiration
Subjective Assessment: Nurses interview the patient to gather information directly during the subjective assessment. It includes questions about the individual's medical history, medications, and symptoms, focusing on past respiratory conditions like...
Respiratory Volumes and Capacities
Respiratory Volumes
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
The Respiratory System
Respiratory Volumes and Capacities I