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Complex functions of Gcn5 and Pcaf in development and disease

Evangelia Koutelou1, Aimee T Farria1, Sharon Y R Dent1

  • 1Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Science Park, Smithville, TX 78957, United States of America; Center for Cancer Epigenetics, University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States of America.

Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms
|July 31, 2020
PubMed
Summary

GCN5 and PCAF (lysine acetyltransferases) are key in gene activation and development. Their roles in vertebrate development and oncogenesis are crucial for understanding disease states.

Keywords:
CancerChromatinDevelopmentGcn5Pcaf

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