Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nuclear Transmutation03:20

Nuclear Transmutation

20.2K
Nuclear transmutation is the conversion of one nuclide into another. It can occur by the radioactive decay of a nucleus, or the reaction of a nucleus with another particle. The first manmade nucleus was produced in Ernest Rutherford’s laboratory in 1919 by a transmutation reaction, the bombardment of one type of nuclei with other nuclei or with neutrons. Rutherford bombarded nitrogen-14 atoms with high-speed α particles from a natural radioactive isotope of radium and observed...
20.2K
Types of Radioactivity03:23

Types of Radioactivity

19.1K
The most common types of radioactivity are α decay, β decay, γ decay, neutron emission, and electron capture.
Alpha (α) decay is the emission of an α particle from the nucleus. For example, polonium-210 undergoes α decay:
19.1K
Isotopes and Radioisotopes01:28

Isotopes and Radioisotopes

10.7K
In the early 1900s, English chemist Frederick Soddy realized that an element could have atoms with different masses that were chemically indistinguishable. These different types are called isotopes — atoms of the same element that differ in mass. Isotopes differ in mass because they have different numbers of neutrons but are chemically identical because they have the same number of protons. Soddy was awarded the Nobel Prize in Chemistry in 1921 for this discovery.
An isotope containing...
10.7K
Positron Emission Tomography01:29

Positron Emission Tomography

6.7K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
6.7K
Radiation: Applications01:17

Radiation: Applications

1.6K
The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Combined Photon and Carbon Ion Radiation Therapy for Sinonasal Malignancies: Results of the HIT-SNT Prospective Phase 2 Trial.

International journal of radiation oncology, biology, physics·2023
Same author

Geriatric Radiation Oncology: What We Know and What Can We Do Better?

Clinical interventions in aging·2023
Same author

Transmigration of macrophages through primary adult rat Sertoli cells.

Tissue barriers·2022
Same author

Carbon Ion Beam Boost Irradiation in Malignant Tumors of the Nasal Vestibule and the Anterior Nasal Cavity as an Organ-Preserving Therapy.

Frontiers in oncology·2022
Same author

<i>In Silico</i> Feasibility Study of Carbon Ion Radiotherapy With Simultaneous Integrated Boost for Head and Neck Adenoid Cystic Carcinoma.

Frontiers in oncology·2021
Same author

Long-Term Maintenance of Viable Adult Rat Sertoli Cells Able to Establish Testis Barrier Components and Function in Response to Androgens.

Cells·2021

Related Experiment Video

Updated: Dec 13, 2025

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

20.8K

Particle Therapy: Protons and Heavy Ions.

Alexandra D Jensen1

  • 1Department of Radiation Oncology, University Hospitals Giessen and Marburg (UKGM), Marburg, Germany, alexdjensen@gmx.de.

Advances in Oto-Rhino-Laryngology
|July 31, 2020
PubMed
Summary

Particle therapy offers highly conformal radiotherapy for head and neck cancers. This advanced treatment protects critical structures while delivering precise radiation doses to tumors in the paranasal sinus and anterior skull base.

Area of Science:

  • Oncology
  • Radiation Oncology
  • Medical Physics

Background:

  • Particle therapy is an advanced radiotherapy technique enabling precise dose delivery.
  • Its conformality is particularly beneficial for complex anatomical regions like the head and neck.
  • Head and neck malignancies, especially those in the paranasal sinus and anterior skull base, present unique treatment challenges due to proximity to critical structures.

Purpose of the Study:

  • To explore the rationale behind using particle therapy for head and neck malignancies.
  • To review the clinical experience with particle therapy in treating paranasal sinus and anterior skull base tumors.
  • To summarize the potential of particle therapy for re-irradiation in these specific tumor sites.

Main Methods:

  • Literature review of particle therapy applications in head and neck oncology.

More Related Videos

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
09:49

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods

Published on: April 24, 2020

10.3K
Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
07:57

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

3.0K

Related Experiment Videos

Last Updated: Dec 13, 2025

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

20.8K
A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
09:49

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods

Published on: April 24, 2020

10.3K
Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
07:57

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

3.0K
  • Analysis of clinical outcomes for patients treated with particle therapy for paranasal sinus and anterior skull base tumors.
  • Evaluation of treatment planning capabilities and dose distribution advantages of particle therapy.

    • Main Results:

    • Particle therapy allows for highly conformal dose distributions, sparing organs at risk.
    • Clinical data suggests favorable outcomes and toxicity profiles for particle therapy in treated malignancies.
    • The technique shows promise for managing complex cases and re-irradiation scenarios.

    Conclusions:

    • Particle therapy is a valuable tool for treating head and neck malignancies, particularly in the paranasal sinus and anterior skull base.
    • It facilitates high-dose tumor irradiation while preserving normal tissue tolerance.
    • Further investigation into its role in re-irradiation is warranted.