Combined two-centre experience of single-entry telescopic rods identifies characteristic modes of failure

India Cox1, Louay Al Mouazzen1, Sabri Bleibleh2

  • 1Bristol Royal Hospital for Children, Bristol, UK.

Insights

The Fassier Duval (FD) rod for osteogenesis imperfecta (OI) shows high revision rates, similar to older implants. Fixation issues in the femur and tibia are common, especially in younger children, necessitating future implant improvements.

Area of Science:

  • Pediatric Orthopedics
  • Biomaterials Science
  • Skeletal Dysplasias

Background:

  • Osteogenesis imperfecta (OI) is a genetic disorder characterized by brittle bones.
  • Telescopic intramedullary rods are used to stabilize long bones in children with severe OI.
  • The Fassier Duval (FD) rod is a third-generation implant designed for easier insertion.

Purpose of the Study:

  • To evaluate the clinical outcomes and implant survival of the Fassier Duval (FD) rod in children with severe osteogenesis imperfecta (OI).
  • To identify complications and failure modes associated with FD rod implantation.
  • To compare the performance of FD rods with previous generations of telescopic implants.

Main Methods:

  • A retrospective review of 34 children with severe OI treated with FD rods in 72 lower limb long bones.
  • Prospective data collection with a follow-up period of 1.5 to 11 years.
  • Analysis of implant survival rates, revision rates, and specific complications such as rod bending, refractures, and fixation failures.

Main Results:

  • A 33% revision rate was observed, with 11 rods bending and causing refractures.
  • Proximal femoral and distal tibial fixation failures were common.
  • The five-year survival rate for femoral rods was 63% and for tibial rods was 64%.

Conclusions:

  • FD rods offer easier implantation but do not surpass the revision rates of second-generation implants.
  • Proximal femoral fixation is problematic in younger children, and distal tibial fixation failures occur frequently.
  • Future implant designs must address fixation challenges in the proximal femur and distal tibia to reduce complications in OI patients.
Abstract

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