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Ocular Syphilis Causing Panophthalmitis
Basil Mathews1, Roshan George, Jan Niklas Ulrich
1Department of Ophthalmology, Kittner Eye Center, University of North Carolina, Chapel Hill, North Carolina, U.S.A.
Ophthalmic Plastic and Reconstructive Surgery
|August 1, 2020
Summary
Ocular syphilis, a resurgence-driven infection, can cause severe eye inflammation like panophthalmitis. Prompt diagnosis and treatment with antibiotics, including penicillin, are crucial for preventing vision loss.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Bacteriology
Background:
- Syphilis, caused by Treponema pallidum, is experiencing a global resurgence.
- Ocular syphilis is a rare but serious manifestation of the infection.
- Orbital cellulitis can be an initial presentation of ocular syphilis.
Purpose of the Study:
- To report a case of ocular syphilis presenting as orbital cellulitis.
- To highlight the importance of recognizing ocular syphilis in clinical practice.
- To emphasize the effectiveness of timely treatment in preventing visual sequelae.
Main Methods:
- Case report of a 30-year-old female with orbital cellulitis.
- Diagnostic workup for infectious and inflammatory conditions.
- Treatment regimen including intravenous penicillin, broad-spectrum antibiotics, topical steroids, and cycloplegia.
Main Results:
- The patient was diagnosed with ocular syphilis leading to panophthalmitis.
- Full recovery was achieved following the prescribed treatment.
- No visual sequelae were reported post-treatment.
Conclusions:
- Ocular syphilis requires prompt recognition and management to prevent vision loss.
- Intravenous penicillin remains a cornerstone in treating ocular syphilis.
- Healthcare professionals must maintain a high index of suspicion for syphilis in patients with unexplained orbital inflammation.
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