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Published on: July 7, 2016
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Interventional Pharmacoeconomics
Daniel A Goldstein, Garth W Strohbehn, Anthony V Serritella1
1Section of Hematology/Oncology, University of Chicago Medicine, Chicago, IL.
Cancer Journal (Sudbury, Mass.)
|August 1, 2020
Summary
Rising oncology drug costs challenge healthcare. Developing lower-cost, off-label treatments using pharmacologic rationale offers an economically impactful alternative solution.
Area of Science:
- Health Economics
- Oncology
- Pharmacology
Background:
- Increasing healthcare costs pose a global challenge, particularly in the United States.
- The escalating price of oncology drugs significantly contributes to rising healthcare expenditures.
- Current solutions often focus on broad health policy changes.
Purpose of the Study:
- To introduce and describe the approach of interventional pharmacoeconomics.
- To present off-label treatment regimens as a viable strategy for reducing oncology drug costs.
- To highlight the economic impact of pharmacologically-guided treatment selection.
Main Methods:
- Identifying drugs with suitable pharmacologic and clinical properties for alternative uses.
- Developing evidence-based, lower-cost off-label treatment regimens.
- Analyzing the potential economic impact of these alternative regimens.
Main Results:
- Demonstrated the feasibility of using existing drugs in novel, cost-effective ways.
- Provided multiple examples of successful interventional pharmacoeconomics strategies.
- Highlighted significant potential for cost savings in cancer care.
Conclusions:
- Interventional pharmacoeconomics offers a practical alternative to traditional health policy changes for managing drug costs.
- Off-label treatment strategies, when based on sound pharmacologic principles, can lead to substantial economic benefits.
- This approach has the potential to improve the affordability of cancer care.
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