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Integration Between Cerebral Hemispheres Contributes to Defense Mechanisms.

Sergio Paradiso1, Warren S Brown2,3, John H Porcerelli4

  • 1Institute of Cognitive and Translational Neuroscience, INECO Foundation, Favaloro University, CONICET, Buenos Aires, Argentina.

Frontiers in Psychology
|August 1, 2020
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Summary

Individuals without a corpus callosum (agenesis of the corpus callosum; AgCC) show less mature defense mechanisms. This suggests interhemispheric integration is crucial for developing healthy defense mechanisms.

Keywords:
agenesis of the corpus callosumconnectivitycorpus callosumdefense mechanismsinterhemispheric transfer

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Area of Science:

  • Neuroscience
  • Psychology
  • Developmental Psychology

Background:

  • Defense mechanisms are crucial for psychological coping.
  • The neural basis of defense mechanism development remains largely unknown.
  • Interhemispheric integration may play a role in mature defense mechanisms.

Purpose of the Study:

  • To investigate the role of interhemispheric integration in defense mechanism development.
  • To examine defense mechanism use in individuals with agenesis of the corpus callosum (AgCC).

Main Methods:

  • Compared defense mechanism use in adults with AgCC (N=27) and matched healthy controls (N=30).
  • Assessed defense mechanisms (denial, projection, identification) using Thematic Apperception Test narratives scored by the Defense Mechanism Manual.
  • Analyzed defense mechanism maturity across developmental levels.

Main Results:

  • Individuals with AgCC exhibited greater use of immature defense mechanisms (denial) and less use of mature mechanisms (identification) compared to controls.
  • These differences were evident after age 18, suggesting a disruption in mature defense development.
  • Findings characterize social and emotional processing in AgCC.

Conclusions:

  • Functional integration across brain hemispheres is important for the development of defense mechanisms.
  • AgCC is associated with altered defense mechanism profiles, highlighting the role of the corpus callosum.
  • Results support the hypothesis linking interhemispheric integration to defense mechanism maturation.