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Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
Published on: February 2, 2024
Mycobacterium mageritense Prosthetic Joint Infection
Maria A Caravedo Martinez1, Lucas S Blanton1
1Department of Internal Medicine, Division of Infectious Diseases, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77550-0435, USA.
Abstract:
Prosthetic joint infections (PJI) complicate up to 2% of arthroplasties and are usually caused by typical bacterial agents (e.g., staphylococci and streptococci). Although an infrequent cause of PJI, mycobacterial species are difficult to eradicate, as they adhere to hardware, form biofilms, and have high rates of antimicrobial resistance. Mycobacterium mageritense is a rapidly growing Mycobacterium that has been infrequently described as a cause of surgical and device-related infections. We herein described a case of prosthetic knee infection due to M. mageritense. The patient was treated with removal of hardware, antimicrobials, and prosthetic knee reimplantation with a good outcome. To our knowledge, M. mageritense has not been previously described as a cause of PJI in the medical literature.
Insights
This study reports a rare case of prosthetic knee infection caused by Mycobacterium mageritense. Prompt treatment involving hardware removal and antimicrobials led to a successful outcome in this prosthetic joint infection.
Area of Science:
- Infectious Diseases
- Orthopedic Surgery
- Microbiology
Background:
- Prosthetic joint infections (PJI) affect up to 2% of arthroplasties, typically caused by bacteria.
- Mycobacterial species, though infrequent, pose challenges in PJI due to biofilm formation and antimicrobial resistance.
- Mycobacterium mageritense is a rapidly growing mycobacterium rarely implicated in device-related infections.
Observation:
- A case of prosthetic knee infection caused by Mycobacterium mageritense is presented.
- Mycobacterium mageritense is a rapidly growing mycobacterium rarely implicated in surgical or device-related infections.
Findings:
- The patient with prosthetic knee infection due to M. mageritense underwent successful treatment.
- Treatment involved hardware removal, antimicrobial therapy, and prosthetic knee reimplantation.
Implications:
- This case expands the known spectrum of pathogens causing prosthetic joint infections.
- Mycobacterium mageritense should be considered in the differential diagnosis of recalcitrant prosthetic joint infections.
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