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Efficacy and Safety of Intranasal Medical Management in Pediatric Patients with Idiopathic Recurrent Epistaxis
Osman Ilkay Ozdamar1, Gul Ozbilen Acar1
1Istanbul Medeniyet University Goztepe Training and Research Hospital, Department of Otorhinolaryngology Head and Neck Surgery, Istanbul, Turkey.
Insights
Topical intranasal antimicrobial ointment and moisturizing gel effectively treat recurrent pediatric epistaxis. This non-invasive approach is recommended before considering more invasive interventions for nosebleeds.
Area of Science:
- Otolaryngology
- Pediatric Medicine
- Dermatology
Background:
- Idiopathic recurrent epistaxis is common in children.
- Previous treatments often involve invasive methods.
- A need exists for safe, effective first-line management.
Purpose of the Study:
- To evaluate the efficacy and safety of topical intranasal antimicrobial and moisturizing agents.
- To establish this combination as a first-step treatment for pediatric epistaxis.
- To assess outcomes in patients with hyperemic versus hypervascular nasal mucosa.
Main Methods:
- Retrospective chart review of 326 pediatric patients with recurrent epistaxis.
- Enrolled 67 patients, divided into hyperemic (35) and hypervascular (32) nasal mucosa groups.
- Assessed recurrence rates after intranasal antimicrobial and moisturizing agent treatment.
Main Results:
- No statistically significant difference in epistaxis recurrence between hyperemic (22.9%) and hypervascular (34.4%) groups.
- Treatment showed comparable outcomes regardless of initial nasal mucosa appearance.
- The intervention was well-tolerated in the pediatric cohort (ages 3-17).
Conclusions:
- Intranasal antimicrobial ointment and moisturizing gel are effective, non-invasive treatments for pediatric idiopathic recurrent epistaxis.
- This medical management is a suitable first-line option prior to invasive procedures.
- The treatment approach offers a safe and easily applicable solution for childhood nosebleeds.
Objective:
The goal of the study was to verify the efficacy and safety of topical medical treatment in idiopathic recurrent pediatric epistaxis patients by intranasal usage of both an antimicrobial and a moisturizing agent as a first-step management modality.
Method:
Sixty-seven out of 326 pediatric patients with idiopathic recurrent epistaxis selected on a chart review of follow-up were enrolled in the study. The study was designed as an analysis of two groups: one group included 35 individuals (52.2% of the total cohort) having a hyperemic nasal mucosa and the second group included 32 individuals (47.8% of the total cohort) having a hypervascular nasal mucosa on physical examination before treatment.
Results:
The study was performed with a total of 67 children (age range 3-17 years) including 36 males (53.7% of total cohort) and 31 females (46.3% of total cohort). The mean age was 9.78±4.09 years. There was not any statistically significant difference between the groups in terms of age, duration of follow-up and recurrence time of epistaxis (p>0.05). Recurrence of epistaxis was seen in 22.9% (8/35) of hyperemic nasal mucosa group and in 34.4% (11/32) of hypervascular nasal mucosa group (p>0.05).
Conclusion:
We advise the use of both an intranasal antimicrobial ointment and a mucosal moisturizing gel as an effective, noninvasive and easily applicable medical treatment option for pediatric patients with idiopathic recurrent epistaxis before more invasive methods of epistaxis control.
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