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Capillary electrophoresis.

S W Compton1, R G Brownlee

  • 1Marketing Services Management, Vallejo, CA 94590.

Biotechniques
|May 1, 1988
PubMed
Summary

Capillary electrophoresis (CE) is a powerful separation technique. With recent instrumentation advances and upcoming commercial availability, CE is poised for routine application in diverse analytical, research, and clinical settings.

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Area of Science:

  • Analytical Chemistry
  • Separation Science
  • Biotechnology

Background:

  • Capillary electrophoresis (CE) and related techniques have a long history but have seen recent growth in recognition.
  • Historically, CE usage was concentrated among analytical chemists in specific regions and research groups.
  • Basic instrumentation challenges for CE have only recently been addressed.

Purpose of the Study:

  • To highlight the growing versatility and potential applications of capillary electrophoresis.
  • To discuss the transition of CE from an academic tool to a routine analytical method.
  • To emphasize the impact of standardized commercial instrumentation on CE adoption.

Main Methods:

  • Review of historical and recent developments in capillary electrophoresis instrumentation.
  • Analysis of the current research trends focusing on specific CE applications.
  • Anticipation of the impact of commercialization on the field.

Main Results:

  • Researchers are actively exploring diverse applications of CE, showcasing its potential.
  • Standardized commercial instrumentation for CE is nearing availability.
  • The technique is moving beyond academic research towards practical use.

Conclusions:

  • Capillary electrophoresis is evolving into a versatile tool for routine separations.
  • The advent of commercial instrumentation will significantly broaden CE's accessibility and utility.
  • CE is expected to become valuable for analysts, researchers, and clinicians across various fields.

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