An Exercise Program for Peritoneal Dialysis Patients in the United States: A Feasibility Study

Area of Science:

• Nephrology
• Exercise Physiology
• Gerontology

Background:

• Patients with end-stage kidney disease on peritoneal dialysis (PD) often experience physical inactivity and frailty.
• Existing research on exercise interventions for PD patients is limited, with no established programs in the United States.
• Physical deterioration is a significant concern for individuals undergoing PD therapy.

Purpose of the Study:

• To assess the feasibility of a combined resistance and cardiovascular exercise program for PD patients.
• To evaluate the safety and adherence of a structured exercise regimen in a US-based home dialysis center.

Main Methods:

• A parallel randomized controlled feasibility study was conducted.
• 18 PD patients were assigned to an intervention group (exercise) and 18 to a control group (standard care).
• The intervention included monthly consultations, prescribed exercises using bands, and telephone support over 12 weeks.

Main Results:

• Feasibility was assessed via eligibility (76%), recruitment (63%), retention (72%), and adherence (77%) rates.
• The exercise group showed significant improvements in the timed-up-and-go test (P=0.04) and appetite (P=0.04).
• No serious adverse events related to the exercise program were reported, indicating good safety.

Conclusions:

• A combined resistance and cardiovascular exercise program is feasible and safe for PD patients.
• The findings support the integration of exercise programs, coordinated by professionals, into PD therapy.
• Such programs can help reduce physical deterioration associated with PD.