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Updated: Dec 13, 2025
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Experimental Approaches to Tissue Engineering
Published on: August 30, 2007
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Tissue engineering: from the bedside to the bench and back to the bedside
Tatevik Sahakyants1, Joseph P Vacanti2
1Laboratory for Tissue Engineering and Organ Fabrication, Massachusetts General Hospital (MGH), 3D BioLabs, LLC, 700 Main Street, Cambridge, MA, 02139, USA.
Pediatric Surgery International
|August 1, 2020
Summary
Tissue Engineering and Regenerative Medicine has advanced significantly, driven by clinical needs and pediatric surgical challenges. This field shows promise, with therapies moving from lab to patient care, especially for children.
Area of Science:
- Tissue Engineering
- Regenerative Medicine
- Biomedical Engineering
Background:
- The field has seen rapid evolution over 30 years.
- Progress is viewed through clinical needs, laboratory science, and patient application.
- Pediatric surgical problems have been a key driver for innovation.
Purpose of the Study:
- To review the history, current status, and future direction of Tissue Engineering and Regenerative Medicine.
- To highlight the journey from laboratory research to clinical application.
- To emphasize the role of pediatric surgery in advancing the field.
Main Methods:
- Literature review summarizing key developments.
- Analysis of the progression from scientific discovery to patient treatment.
- Focus on the translation of research into clinical practice.
Main Results:
- Significant progress has been made, though the field's full potential is yet to be realized.
- Several therapies have successfully transitioned from concept to human application.
- Many advancements have been applied in the surgical care of children.
Conclusions:
- Tissue Engineering and Regenerative Medicine is a dynamic field with a strong foundation in addressing clinical needs.
- The interdisciplinary approach involving science, engineering, and medicine is crucial for success.
- The field holds great promise for future therapeutic interventions, particularly in pediatric surgery.
