Selective Detection of Methomyl Pesticide by a Catalytic Chemosensing Assay

The catalytic chemosensing assay (CCA), a new indicator displacement assay, was developed for selective detection of methomyl, a highly toxic pesticide. Trimetallic complex {[Fe^II (dmbpy)(CN)₄ ]-[Pt^II (DMSO)Cl]₂ -[Ru^II (bpy)₂ (CN)₂ ]} (1; dmbpy=4,4'-dimethyl-2,2'-bipyridine, bpy=2,2'-bipyridine) was synthesized as a task-specific catalyst to initially reduce and degrade methomyl to CH₃ SH/CH₃ NH₂ /CH₃ CN/CO₂ . The thus-produced CH₃ SH interacts with the trimetallic complex to displace the cis-[Ru^II (bpy)₂ (CN)₂ ] luminophore for monitoring. Other pesticides, including organophosphates and similar carbamate pesticides, remained intact under the same catalytic conditions; a selective sensing signal is only activated when 1 recognizes methomyl. Furthermore, 1 can be applied to detect methomyl in real water samples. In the luminescent mode of the assay, the method detection limit (MDL) of 1 for methomyl (LD₅₀ =17 mg kg^-1 ) was 1.12 mg L^-1 .