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Non-invasive continuous-time glucose monitoring system using a chipless printable sensor based on split ring
Masoud Baghelani1,2,3, Zahra Abbasi4, Mojgan Daneshmand4
1Microwave to Millimeter Wave (M2M) Lab., Department of Electrical and Computer Engineering, University of Alberta, Edmonton, AB, Canada. baghelan@ualberta.ca.
Scientific Reports
|August 2, 2020
Summary
This study introduces a novel, power-free sensor for non-invasive glucose monitoring in interstitial fluid. The chip-less tag, integrated with a smartwatch reader, offers high sensitivity for real-time blood glucose tracking.
Area of Science:
- Biomedical Engineering
- Sensor Technology
- Wearable Technology
Background:
- Continuous glucose monitoring (CGM) is crucial for diabetes management.
- Existing CGM methods often require invasive procedures or have limitations in accuracy and power consumption.
Purpose of the Study:
- To develop a highly sensitive, non-invasive, and power-free sensor for real-time glucose monitoring.
- To integrate this sensor into a wearable device, such as a smartwatch, for patient convenience.
Main Methods:
- A chip-less tag sensor design utilizing electromagnetic coupling with a reader.
- The sensor is energized wirelessly and its frequency response is analyzed.
- Testing involved measuring glucose concentrations in saline solutions mimicking interstitial fluid.
Main Results:
- The sensor achieved high sensitivity, detecting glucose concentration changes with approximately 1 mM/l accuracy.
- A resonance frequency shift of 38 kHz was observed over the physiological glucose range.
- The sensor design demonstrated extended field concentration for enhanced sensitivity.
Conclusions:
- The developed sensor offers a promising non-invasive, power-free solution for real-time glucose monitoring.
- The technology has the potential for seamless integration into wearable devices like smartwatches.
- Further investigation confirmed negligible interference from physiological electrolyte variations.

