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Whole Mount in Situ Hybridization of E8.5 to E11.5 Mouse Embryos
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Published on: October 10, 2011

Detection of H-2K mRNA in mouse 8-cell embryo by cDNA cloning

T Nagata1, M Nozaki, T Morita

  • 1Department of Microbial Genetics, Osaka University.

Idengaku Zasshi
|October 1, 1988
PubMed

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In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.