Future directions in cardiovascular disease risk prediction

Jenny A Doust1, Carissa Bonner2, Katy JL Bell3

  • 1BMBS, PhD, FRACGP, Clinical Professorial Research Fellow, Centre for Longitudinal and Life Course Research, School of Public Health, University of Queensland, Qld.

Insights

Improving cardiovascular disease (CVD) prevention requires better use of risk prediction tools. Updated calculators and shared decision-making can help identify high-risk individuals and optimize preventive medication, reducing CVD events.

Area of Science:

  • Cardiovascular disease prevention
  • Health informatics
  • Medical decision making

Background:

  • National Vascular Disease Prevention Alliance (NVDPA) guidelines for cardiovascular disease (CVD) risk were published in 2012.
  • Many high-risk individuals are not prescribed preventive medication or have CVD risk factors unrecorded.
  • Improved CVD risk assessment and medication targeting can reduce disease incidence.

Purpose of the Study:

  • To review recent developments in cardiovascular disease (CVD) risk prediction.
  • To examine calculators from the USA, UK, and New Zealand.
  • To assess non-traditional tests for cardiovascular risk.

Main Methods:

  • Review of recent cardiovascular disease (CVD) risk prediction tools.
  • Evaluation of international risk calculators (USA, UK, New Zealand).
  • Assessment of non-traditional cardiovascular risk assessment methods.

Main Results:

  • The Framingham Risk Equation overestimates risk in contemporary Australian populations.
  • Newer risk calculators demonstrate improved calibration.
  • Shared decision-making tools aid in clarifying the perceived benefits of medication.

Conclusions:

  • Current CVD risk prediction tools require refinement for contemporary populations.
  • Enhanced risk assessment and shared decision-making can improve preventive strategies.
  • Optimizing medication use based on accurate risk prediction is crucial for CVD reduction.
Abstract

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