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Diverse allosteric componentry and mechanisms control entry into aromatic metabolite biosynthesis

Wanting Jiao1, Eric Jm Lang2, Yu Bai1

  • 1Ferrier Research Institute, Victoria University of Wellington, Wellington, New Zealand; Maurice Wilkins Centre for Molecular Biodiscovery, Biomolecular Interaction Centre, University of Canterbury, Christchurch, New Zealand.

Current Opinion in Structural Biology
|August 3, 2020
PubMed
Summary

Allosteric regulation of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase (DAH7PS) controls aromatic amino acid synthesis. This review explores the structural and evolutionary basis of DAH7PS allosteric control mechanisms across diverse organisms.

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