Jove
Visualize
Contact Us

Related Concept Videos

Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

3.5K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
3.5K
Antibiotic Selection00:57

Antibiotic Selection

58.8K
Overview
58.8K
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

169
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
169
Urine Studies II: Urine Culture and Sensitivity Test01:26

Urine Studies II: Urine Culture and Sensitivity Test

498
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
498
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

191
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
191
Dosage Interval and Administration Route: Determination Methods01:19

Dosage Interval and Administration Route: Determination Methods

118
A medication’s effectiveness largely depends on its appropriate dosage and the route of administration. Dosage ensures that a sufficient drug concentration is maintained in the bloodstream to elicit the desired therapeutic effect without causing toxicity. The route of administration affects the drug's bioavailability, rate of absorption, and onset of action, which are crucial for achieving optimal therapeutic outcomes. Drug dosage calculations are critical to tailoring therapy to...
118

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessing antimicrobial stewardship governance in Northeast Brazilian hospitals: a survey-based analysis.

JAC-antimicrobial resistance·2024
Same author

Epidemiology of Gram-negative bacteria during coronavirus disease 2019. What is the real pandemic?

Current opinion in infectious diseases·2022
Same author

Antimicrobial Stewardship: Leveraging the "Butterfly Effect" of Hand Hygiene.

Antibiotics (Basel, Switzerland)·2022
Same author

Microbiology Assessments in Critically Ill Patients.

Seminars in respiratory and critical care medicine·2022
Same author

Organophosphate poisoning - shadow-boxing in the intensive care unit.

African journal of thoracic and critical care medicine·2021
Same author

Clinical management of severe infections caused by carbapenem-resistant gram-negative bacteria: a worldwide cross-sectional survey addressing the use of antibiotic combinations.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2021
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Dec 13, 2025

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

13.2K

Best practice: antibiotic decision-making in ICUs.

Adrian John Brink1, Guy Richards2

  • 1Division of Medical Microbiology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

Current Opinion in Critical Care
|August 3, 2020
PubMed
Summary
This summary is machine-generated.

Optimizing antibiotic use in the ICU involves limiting exposure duration and assessing resistance risk before initiating treatment. Best practices focus on reducing unnecessary antibiotic exposure to combat resistance development.

More Related Videos

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
12:03

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method

Published on: April 18, 2019

27.3K
Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
08:58

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

7.5K

Related Experiment Videos

Last Updated: Dec 13, 2025

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

13.2K
Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
12:03

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method

Published on: April 18, 2019

27.3K
Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
08:58

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

7.5K

Area of Science:

  • Infectious Diseases
  • Critical Care Medicine
  • Antimicrobial Stewardship

Background:

  • Optimizing antibiotic use in Intensive Care Units (ICUs) is a significant clinical challenge.
  • Effective antimicrobial stewardship is crucial for improving patient outcomes and combating antimicrobial resistance.

Purpose of the Study:

  • To review current best practices for antibiotic decision-making in the ICU.
  • To highlight strategies for optimizing antibiotic use and minimizing resistance.

Main Methods:

  • Systematic review of current literature on antibiotic stewardship in ICUs.
  • Analysis of core best practices for antibiotic decision-making, including initiation, duration, and dosing.
  • Evaluation of strategies to mitigate risks associated with antibiotic exposure.

Main Results:

  • Shortest effective antibiotic duration is key; initiation decisions should incorporate resistance risk assessment.
  • Delayed antibiotic initiation may be considered in select sepsis cases pending sensitivity data.
  • Empiric antibiotic choices should be guided by syndromic antibiograms and institutional protocols, pending validated stratification scores for multidrug-resistant organisms (MDR).
  • Dose optimization and streamlined stewardship practices are essential to minimize negative effects like prolonged therapy and collateral damage from broad-spectrum or sequential antibiotic use.

Conclusions:

  • Reducing unnecessary antibiotic exposure is vital for limiting antimicrobial resistance development.
  • Identifying and implementing optimal stewardship practices in daily ICU care is a priority.
  • Continued research and validation of stratification scores are needed for improved antibiotic decision-making.