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Anaphylaxis to human serum albumin
C T Stafford1, S A Lobel, B C Fruge
1Medical College of Georgia, Augusta.
Summary
A pregnant woman experienced severe allergic reactions during plasmapheresis using 5% human serum albumin (HSA). Testing confirmed an IgE-mediated allergy to HSA, highlighting potential risks in specific patient populations.
Area of Science:
- Immunology
- Allergy and Immunology
- Clinical Medicine
Background:
- Plasmapheresis is a medical procedure to remove plasma from the blood.
- Human serum albumin (HSA) is commonly used as a plasma substitute or adjunct in medical treatments.
- Adverse reactions to HSA during medical procedures can occur, necessitating investigation into their immunological basis.