Related Experiment Video
Updated: Dec 13, 2025

07:18
Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
2.0K
EVALUATION OF RETINAL VESSEL DIAMETERS IN EYES WITH ACTIVE CENTRAL SEROUS CHORIORETINOPATHY.
Orhan Altunel1, Hasan Basri Arifoglu2
1Department of Ophthalmology, Kutahya Health Sciences University, Evliya Celebi Education and Research Hospital, Kutahya, Turkey ; and.
Retina (Philadelphia, Pa.)
|August 3, 2020
Summary
Retinal venous wall thickness increased and inner diameter narrowed in central serous chorioretinopathy (CSC) eyes compared to healthy eyes. These venous diameter alterations may contribute to CSC pathogenesis.
Area of Science:
- Ophthalmology
- Retinal Imaging
- Vascular Biology
Background:
- Central serous chorioretinopathy (CSC) is a condition affecting the retina.
- Understanding the structural changes in retinal vessels in CSC is crucial for elucidating its pathogenesis.
Purpose of the Study:
- To compare retinal vessel diameters between healthy eyes and eyes with active CSC.
- To investigate the potential role of altered retinal vessel diameters in the pathogenesis of CSC.
Main Methods:
- Retrospective analysis of 39 patients with CSC and 34 healthy controls.
- Spectralis optical coherence tomography + HRA with infrared reflectance imaging was used.
- Retinal artery and vein inner/outer diameters and wall thicknesses were measured around the optic disc.
Main Results:
- Analysis included 304 vessels in CSC eyes and 266 in healthy eyes.
- Venous wall thickness was significantly greater in CSC eyes (40.0 ± 4.9 μm) versus healthy eyes (33.5 ± 4.1 μm).
- Venous inner diameter was significantly narrower in CSC eyes (52.5 ± 9.7 μm) versus healthy eyes (61.3 ± 8.1 μm).
Conclusions:
- Alterations in retinal venous diameter, specifically increased wall thickness and narrowed inner diameter, are observed in active CSC.
- These venous changes may play a role in the pathogenesis of CSC, alongside choroidal thickness changes.

