Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists01:23

Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists

350
Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
350
Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists01:18

Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists

321
Endothelins (ETs) are potent vasoactive peptides critical in the human body's various physiological and pathological processes. One of the most promising therapeutic strategies for treating pulmonary arterial hypertension (PAH) involves counteracting the effects of these endothelins using a class of drugs known as endothelin receptor antagonists.
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme...
321

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A DEB-TACE-Centered Sequential Multimodal Limb-Salvage Strategy for Refractory Upper-Extremity Desmoid-Type Fibromatosis.

Cardiovascular and interventional radiology·2026
Same author

Reading Between the Lines: From the CVIR 2026 Survey Into the Future of (CV)IR.

Cardiovascular and interventional radiology·2026
Same author

European Association of Urology Guidelines on Urethral Strictures: Summary of the 2026 Guidelines. Update in Recommendations for Endoluminal Management of Male Anterior Urethral Strictures.

European urology·2026
Same author

Additive Manufacturing of Nanoscale Multimaterial Voxels Via Meniscus-Confined Electrodeposition.

ACS nano·2026
Same author

Radial Access in Interventional Radiology and the Risk of Stroke: Lessons Learned.

Journal of vascular and interventional radiology : JVIR·2026
Same author

Near-Total Prostate Volume Reduction After Prostatic Artery Embolization With Spontaneous Transition-Zone Sloughing.

Cardiovascular and interventional radiology·2026
Same journal

Reply to "Clarifying Recurrence, Bleeding Risk, and Procedural Burden in Central Renal Tumor Ablation".

Journal of vascular and interventional radiology : JVIR·2026
Same journal

Cryoablation of Abdominal Wall Endometriosis: Evidence Base Calling for Greater Awareness of this Minimally Invasive Option.

Journal of vascular and interventional radiology : JVIR·2026
Same journal

Specially Designed Double-Loop Versus Single-Loop 10.2-Fr Multihole Pigtail Catheters for Pleural Effusion Drainage: A Retrospective Comparative Study of Procedural Efficiency, Catheter Stability, and Safety.

Journal of vascular and interventional radiology : JVIR·2026
Same journal

CT-Based Intratumoral Artery-Like Volume for Pre-Treatment Lung Shunt Estimation in Hepatocellular Carcinoma.

Journal of vascular and interventional radiology : JVIR·2026
Same journal

Socioeconomic Factors Impacting Survival in Patients with Hepatocellular Carcinoma Treated with Locoregional Therapies: A Single-Center Study.

Journal of vascular and interventional radiology : JVIR·2026
Same journal

2026 SIR Dotter Lecturer of the Society of Interventional Radiology Interventional Radiology: A Journey of Creativity.

Journal of vascular and interventional radiology : JVIR·2026
See all related articles

Related Experiment Video

Updated: Dec 13, 2025

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate HoLEP.
06:04

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate HoLEP.

Published on: March 6, 2018

17.4K

Repeat Prostatic Artery Embolization for Patients with Benign Prostatic Hyperplasia.

Nuno V Costa1, Daniel Torres1, João Pisco2

  • 1Interventional Radiology Department, Hospital Saint Louis, Rua Luz Soriano 182, 1200-249 Lisbon, Portugal; Radiology Department, Nova Medical School, Lisbon, Portugal; Interventional Radiology Unit, Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal.

Journal of Vascular and Interventional Radiology : JVIR
|August 4, 2020
PubMed
Summary
This summary is machine-generated.

Repeat prostatic artery embolization (PAE) is safe for recurrent benign prostatic hyperplasia (BPH) symptoms. It is more effective for patients with symptom relapse than for those with no initial response to PAE.

More Related Videos

Retzius-Sparing Robot-Assisted Radical Prostatectomy
12:10

Retzius-Sparing Robot-Assisted Radical Prostatectomy

Published on: May 19, 2022

8.7K
Photoselective Vaporesection of the Prostate via an End-firing Lithium Triborate Crystal Laser
07:17

Photoselective Vaporesection of the Prostate via an End-firing Lithium Triborate Crystal Laser

Published on: May 9, 2018

8.3K

Related Experiment Videos

Last Updated: Dec 13, 2025

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate HoLEP.
06:04

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate HoLEP.

Published on: March 6, 2018

17.4K
Retzius-Sparing Robot-Assisted Radical Prostatectomy
12:10

Retzius-Sparing Robot-Assisted Radical Prostatectomy

Published on: May 19, 2022

8.7K
Photoselective Vaporesection of the Prostate via an End-firing Lithium Triborate Crystal Laser
07:17

Photoselective Vaporesection of the Prostate via an End-firing Lithium Triborate Crystal Laser

Published on: May 9, 2018

8.3K

Area of Science:

  • Urology
  • Interventional Radiology

Background:

  • Benign prostatic hyperplasia (BPH) is a common condition causing lower urinary tract symptoms.
  • Prostatic artery embolization (PAE) is an established treatment for BPH.
  • Repeat PAE may be considered for patients with recurrent or persistent symptoms.

Purpose of the Study:

  • To evaluate the safety and efficacy of repeat prostatic artery embolization (PAE) for benign prostatic hyperplasia (BPH).

Main Methods:

  • A retrospective study of 108 patients with symptomatic BPH treated with repeat PAE.
  • Patients were divided into two groups: those with no initial response (Group A) and those with relapsing symptoms after initial improvement (Group B).
  • Outcomes included technical success, adverse events, International Prostate Symptom Score (IPSS), quality of life (QOL), and clinical success rates.

Main Results:

  • Repeat PAE was performed with a median follow-up of 18 months.
  • No major complications or urinary incontinence were reported.
  • Group B showed significantly greater improvements in IPSS and QOL compared to Group A.
  • Clinical success rates at 12 months were 56.7% for Group B and 28.2% for Group A.

Conclusions:

  • Repeat PAE is a safe and effective treatment option for patients experiencing recurrent lower urinary tract symptoms due to BPH.
  • The efficacy of repeat PAE is significantly higher in patients with symptom relapse compared to those who did not respond to the initial procedure.