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Major Thrombotic Event Despite Anticoagulation in a Patient With COVID-19

Basma Ataallah1,2, Aman Sharma1, Sharmiz Tamanna2

  • 1Internal Medicine, Zucker School of Medicine at Mather, Port Jefferson, USA.

Cureus
|August 4, 2020
PubMed

Insights

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause dangerous blood clots like pulmonary embolism, even with preventative anticoagulation. This case highlights the risk in young COVID-19 patients.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Pulmonology

Background:

  • Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is linked to thromboembolic events.
  • The incidence of these thrombotic complications is not well-documented.
  • Cytokine activation and inflammation are suspected contributors to COVID-19-related thromboembolism.

Observation:

  • A young male patient was diagnosed with COVID-19.
  • He was admitted to the hospital and received two weeks of treatment.
  • Despite being on prophylactic anticoagulation, he developed an acute, severe bilateral saddle pulmonary embolism.

Findings:

  • The case illustrates a severe thrombotic complication in a young COVID-19 patient.
  • Pulmonary embolism occurred despite prophylactic anticoagulation measures.
  • The patient showed significant improvement after treatment.

Implications:

  • This case underscores the significant risk of thromboembolism in COVID-19 patients, irrespective of age or prophylactic treatment.
  • Further research is needed to understand and manage COVID-19-associated thrombotic risks.
  • Clinical vigilance for thromboembolic events in COVID-19 patients is crucial.

Keywords:
coagulopathycovid-19pulmonary embolismtherapeutic anticoagulationthrombosis

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