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Primary diffuse large B-cell lymphoma of the ileal conduit created after radical cystectomy
Takashi Nagai1, Takehiko Okamura1, Komei Katayama1
1Department of Urology Anjo Kosei Hospital Anjo Japan.
Introduction:
Creation of an ileal conduit is associated with complications. A few cases have been reported on tumor development in an ileal conduit; diffuse large B-cell lymphoma originating from an ileal conduit is extremely rare.
Case Presentation:
A 62-year-old Japanese man who had undergone radical cystectomy and ileal conduit diversion 6 years previously presented with a whitish bulge that had developed on the surface of the ileal conduit during follow-up visit. Mass biopsy was performed and the histological diagnosis was diffuse large B-cell lymphoma. Positron emission tomography showed no metastatic lesions. We attempted chemotherapy because the tumor cells tested positive for CD20; after six courses of a regimen involving rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone; diffuse large B-cell lymphoma of the ileal conduit resolved gradually. The patient is alive and remains free from the diagnosed diffuse large B-cell lymphoma.
Conclusion:
We reported an extremely rare case of diffuse large B-cell lymphoma originating from the ileal conduit created after radical cystectomy.
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