Related Experiment Video
Updated: Dec 13, 2025

Focal Laser Ablation of Prostate Cancer: An Office Procedure
Published on: March 30, 2021
Localized prostate cancer with pelvic arteriovenous malformation treated with low-dose-rate brachytherapy after
Takuya Owari1, Nobumichi Tanaka1, Yasushi Nakai1
1Department of Urology Nara Medical University Kashihara, Nara Japan.
Background:
We describe two patients who underwent low-dose-rate prostate brachytherapy after embolization for pelvic arteriovenous malformation.
Case Presentation:
Case 1: A 76-year-old man was referred for definitive treatment of intermediate-risk prostate cancer (prostate-specific antigen 8.667 ng/mL, cT2aN0M0, Gleason score 3 + 4 = 7). We planned low-dose-rate brachytherapy. However, magnetic resonance imaging and computed tomography demonstrated a large pelvic arteriovenous malformation. We performed embolization of the arteriovenous malformation before initiating treatment to lower the risk of rupture of the arteriovenous malformation during low-dose-rate brachytherapy. Case 2: A 69-year-old man was referred for the definitive treatment of high-risk prostate cancer (prostate-specific antigen 5.81 ng/mL, cT2aN0M0, Gleason score 4 + 4 = 8) with a pelvic arteriovenous malformation. Similar to Case 1, we performed embolization of the arteriovenous malformation before initiating treatment. In both cases, low-dose-rate brachytherapy could be performed without complications.
Conclusions:
Low-dose-rate brachytherapy after transcatheter embolization of pelvic arteriovenous malformations can safely and effectively treat localized prostate cancer with pelvic arteriovenous malformations.

